Dr. Heike Seybold

Zwei Studenten und eine Tasse Kaffee

Research interests


The immune system of living organisms is one of natures amazing inventions - and so are the strategies of pathogens to overcome it. Ever since I heard about the immune system of plants and the strategies of plant pathogens to outwit these barriers I was fascinated and wanted to learn more about it.
In the Stukenbrock lab I am studying the responses of wheat (Triticum aestivum) and a wild relative to infection by the specialized wheat pathogen Zymoseptoria tritici using phenotypic as well as molecular and biochemical assays. My approach involves wheat cultivars of differential susceptibilities as well as different Z. tritici isolates and mutant strains, giving me the opportunity to look deeper into the underlying mechanisms of infection also on a genetic level.

 

Short CV

 

2016 - present

University Kiel (Germany), PostDoc in the group of Eva Stukenbrock (Environmental Genomics)

2014 - 2016

Free University Berlin (Germany), PostDoc in the group of Tina Romeis (Plant Biochemistry)

2010-2014

Free University Berlin (Germany), PhD student in the group of Tina Romeis (Plant Biochemistry)

2009

3 month internship at the Weizmann Institute of Science (Rehovot, Israel) in the group of Asaph Aharoni (Plant Metabolomics)

2004-2010

University Tübingen (Germany), Diploma in Biochemistry
Diploma Thesis in the group of Birgit Kemmerling/Thorsten Nürnberger (Plant Biochemistry)

 

Publications

 

Seybold H, Boudsocq M, Romeis T. CDPK Activation in PRR Signaling. Methods Mol Biol. 2017;1578:173-183. doi: 10.1007/978-1-4939-6859-6_14.​

Seybold H, Trempel F, Ranf S, Scheel D, Romeis T, Lee J. Ca2+ signalling in plant immune response: from pattern recognition receptors to Ca2+ decoding mechanisms. New Phytol. 2014 Dec;204(4):782-90.

Dubiella U, Seybold H, Durian G, Komander E, Lassig R, Witte CP, Schulze WX, Romeis T. Calcium-dependent protein kinase/NADPH oxidase activation circuit is required for rapid defense signal propagation. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8744-9. doi: 10.1073/pnas.1221294110

Mosher S, Seybold H, Rodriguez P, Stahl M, Davies KA, Dayaratne S, Morillo SA, Wierzba M, Favery B, Keller H, Tax FE, Kemmerling B. The tyrosine-sulfated peptide receptors PSKR1 and PSY1R modify the immunity of Arabidopsis to biotrophic and necrotrophic pathogens in an antagonistic manner. Plant J. 2013 Feb;73(3):469-82. doi: 10.1111/tpj.12050

Itkin M, Seybold H, Breitel D, Rogachev I, Meir S, Aharoni A. TOMATO AGAMOUS-LIKE 1 is a component of the fruit ripening regulatory network. Plant J. 2009 Dec;60(6):1081-95. doi: 10.1111/j.1365-313X.2009.04064.x